نوع مقاله : مقاله کامل علمی - پژوهشی
نویسندگان
1 دانشگاه علوم کشاورزی و منابع طبیعی گرگان
2 Sanio University
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Nanoplastic pollution poses a significant threat to ecosystems and aquatic organisms' health. This study aimed to investigate the protective effects of polyphenols extracted from ivy (Hedera helix) against the damages caused by nanoplastics in Zebrafish (Danio rerio). A two-phase experiment was designed. In the first phase, zebrafish were fed with diets supplemented with polyphenols at levels of 0%, 0.5%, 1%, and 2% for 8 weeks. In the second phase, the treatment groups were exposed to a constant concentration of 1% polyethylene nanoplastics for another 2 weeks while continuing with the same diets. At the end of each phase, samples were collected to assess biochemical parameters such as ALT, ALP, AST, CAT and SOD, as well as the relative expression of SOD and CAT genes. Overall, the results showed that the levels of ALT, ALP, AST, CAT and SOD increased significantly (p<0.05) with increasing polyphenol supplementation in both phases of the experiment. The relative expression of SOD and CAT genes also increased significantly (p<0.05) when polyphenols were supplemented alone or in combination with nanoplastics. This research suggests that ivy polyphenols can be a promising strategy to mitigate oxidative damage caused by nanoplastics and improve the health of aquatic organisms.
کلیدواژهها [English]
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