Sub-lethal effect of pesticide danitol on erythrocyte antioxidant enzymes activity of common carp (Cyprinus carpio)

Document Type : scientific research article

Abstract

Danitol is a non-systemic insecticide, which is used in agriculture. Considering the rare data on danitol toxicity in fish, the aim of this study was to investigate pesticide danitol toxicity in common carp and its effects on erythrocyte antioxidant enzymes activity. For this purpose, the fish were exposed to 0, 0.2, 0.5, 1, 1.5 and 2 mg/l danitol for 96 h; and danitol acute toxicity was found to be 0.47 mg/l according to mortality data. Then, the fish were exposed to 0.05 and 0.1 mg/l danitol for 21 days to investigate chronic effects of danitol on the fish erythrocyte antioxidant enzymes. At the end of the trial, blood samples were taken from different treatments and used for antioxidant enzymes’ activity determination. The results showed that danitol is a “very toxic” substance in common carp. Also, danitiol toxicity decreased superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activity, but not significantly. There was a negative and significant relationship between danitol concentration and antioxidant enzymes’ activity. Overall, it is suggested that danitol toxicity leads oxidative stress in common carp and determination of antioxidant enzymes’ activity is a suitable indicator to monitor the stress.

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Main Subjects


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