Gorgan University of Agricultural Sciences and Natural Resources Journal of Utilization and Cultivation of Aquatics 2345-427X 5 4 2016 12 21 Review of the cytotoxic activity (anticancer) of marine sponges Review of the cytotoxic activity (anticancer) of marine sponges 71 80 3788 10.22069/japu.2017.12344.1331 FA Melika Nazemi Iranian Fisheries Research Institute, Persian Gulf and Oman Sea Ecological Research, Agricultural Research,Education and Extension Organization(AREEO), Bandar Abbas, Iran. Journal Article 2016 12 12 Marine drugs are one of the new ways of the development and manufacture of pharmaceutical products from aquaculture. Cancer is one of the common diseases and the main cause of death in the world. Biological and chemical reviews of sponges have shown that they are a rich source of anticancer compounds. In the case of cytotoxic effect of sponges extensive studies have been done especially in American and European countries. A lot of studies on the Persian Gulf and Oman Sea on sponges are in progress from past decade. The results of this evaluation indicate that sponges: Iophon sp.، Dysidea pallescens ، Ircinia echinata، Dysidea avara، Axinella sinoxeais and Ircina spp of the Persian Gulf and its Islands have cytotoxic effects on cancer cell lines. The cytotoxic properties of marine sponges, it has been proved in many parts of the world and on the other hand, the diversity and abundance of sponge species in the Persian Gulf and Oman Sea reviewed in this scientific evaluation and examined the cytotoxic properties of the marine sponge with emphasis on the sponge in the Persian Gulf. Marine drugs are one of the new ways of the development and manufacture of pharmaceutical products from aquaculture. Cancer is one of the common diseases and the main cause of death in the world. Biological and chemical reviews of sponges have shown that they are a rich source of anticancer compounds. In the case of cytotoxic effect of sponges extensive studies have been done especially in American and European countries. A lot of studies on the Persian Gulf and Oman Sea on sponges are in progress from past decade. The results of this evaluation indicate that sponges: Iophon sp.، Dysidea pallescens ، Ircinia echinata، Dysidea avara، Axinella sinoxeais and Ircina spp of the Persian Gulf and its Islands have cytotoxic effects on cancer cell lines. The cytotoxic properties of marine sponges, it has been proved in many parts of the world and on the other hand, the diversity and abundance of sponge species in the Persian Gulf and Oman Sea reviewed in this scientific evaluation and examined the cytotoxic properties of the marine sponge with emphasis on the sponge in the Persian Gulf. https://japu.gau.ac.ir/article_3788_21d0ac7a3d6d7c7465cdfc47ad10d425.pdf